Israeli police storm al-Aqsa mosque for the second time on Wednesday

Israeli police stormed the al-Aqsa mosque for the second time on Wednesday 

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Israeli police stormed the al-Aqsa mosque in Jerusalem, one of Islam's holiest sites, for the second time on Wednesday, hours after they first raided the compound and arrested hundreds of Palestinians despite condemnations from the Arab and Muslim world.

The clashes, which took place as al-Aqsa sees worshipers offer prayers during the Muslim holy month of Ramadan and Jews celebrate Passover on Wednesday evening, sparked retaliatory rocket fire from militants in Gaza.

During the first incident on Wednesday morning, footage shared on social media showed Israeli officers striking screaming people with batons inside the darkened building. Eyewitnesses told CNN that police had smashed doors and windows to enter the mosque and deployed stun grenades and rubber bullets once inside. Video shared by Israeli police shows forces holding riot shields up as fireworks were launched back at them, ricocheting off the walls.

entered al-Aqsa after "hundreds of rioters and mosque desecrators (had) barricaded themselves" inside. "When the police entered, stones were thrown at them, and fireworks were fired from inside the mosque by a large group of agitators," according to the statement.

The Palestinian Red Crescent in Jerusalem said at least 12 people were injured during clashes in and around the mosque, and at least three of the injured were transferred to hospital, some with injuries from rubber bullets.

The Red Crescent added that at one point its ambulances were targeted by police and were prevented from reaching the injured.

Police said they arrested and removed more than 350 people from the mosque, and that two Israeli police officers were wounded.

Images shared on social media showed dozens of detained people lying facedown on the floor of the mosque with their legs and arms bound behind their backs, and others with their hands tied being led into a vehicle.

During the second incident on Wednesday evening, armed Israeli forces deployed stun grenades and ordered Muslims worshipping there to leave immediately, a video posted to social media shows.

The Israeli police said in a statement that "dozens of law-breaking juveniles, some of them masked" had thrown fireworks and stones into the mosque and tried to barricade themselves inside.

"The police forces prevented the lawbreakers from closing the doors and from barricading themselves (inside) and helped the worshipers leave the Mosque," Israeli police said.

One eyewitness, cameraman Rami Khatib, told CNN that after moving worshippers out of the mosque, the Israeli police had stationed officers at each doorway and prevented people from entering.

The Palestinian Red Crescent in Jerusalem treated six people for their injuries and transferred two of them to the hospital.